Photodynamic Therapy (PDT)
Photodynamic Therapy-Based Dendritic Cell Vaccination Suited to Treat Peritoneal Mesothelioma.
Cancers 2020 February 27 [Link] Trempolec N, Doix B, Degavre C, Brusa D, Bouzin C, Riant O, Feron O Abstract The potential of dendritic cell (DC)-based immunotherapy to treat cancer is, nowadays, well documented. Still, the clinical success of immune checkpoint inhibitors has dampened the interest in anticancer DC vaccination. For highly life-threatening tumors that…
Read MoreLuminol Chemiluminescence Reports Photodynamic Therapy-Generated Neutrophil Activity In Vivo and Serves as a Biomarker of Therapeutic Efficacy.
Photochemistry and Photobiology 2018 October 25 [Link] Davis RW 4th, Snyder E, Miller J, Carter S, Houser C, Klampatsa A, Albelda S, Cengel K, Busch TM Abstract Inflammatory cells, most especially neutrophils, can be a necessary component of the anti-tumor activity occurring after administration of photodynamic therapy. Generation of neutrophil responses has been suggested to…
Read MorePreclinical investigation of folate receptor-targeted nanoparticles for photodynamic therapy of malignant pleural mesothelioma.
International Journal of Oncology 2018 November [Link] Kato T, Jin CS, Lee D, Ujiie H, Fujino K, Hu HP, Wada H, Wu L, Chen J, Weersink RA, Kanno H, Hatanaka Y, Hatanaka KC, Kaga K, Matsui Y, Matsuno Y, De Perrot M, Wilson BC, Zheng G, Yasufuku K Abstract Photodynamic therapy (PDT) following lung-sparing extended…
Read MoreMalignant pleural mesothelioma segmentation for photodynamic therapy planning
Computerized Medical Imaging Society 2017 July [Epub ahead of print] [Link Brahim W, Mestiri M, Betrouni N, Hamrouni K Abstract Medical imaging modalities such as computed tomography (CT) combined with computer-aided diagnostic processing have already become important part of clinical routine specially for pleural diseases. The segmentation of the thoracic cavity represents an extremely important…
Read MoreMalignant pleural mesothelioma segmentation for photodynamic therapy planning
Computerized Medical Imaging Society 2017 July [Epub ahead of print] [Link] Brahim W, Mestiri M, Betrouni N, Hamrouni K Abstract Medical imaging modalities such as computed tomography (CT) combined with computer-aided diagnostic processing have already become important part of clinical routine specially for pleural diseases. The segmentation of the thoracic cavity represents an extremely important…
Read MoreIntraoperative adjuncts for malignant pleural mesothelioma
Translational Lung Cancer Research 2017 June [Link] Chan WH, Sugarbaker DJ, Burt BM Abstract Malignant pleural mesothelioma (MPM) is a rapidly fatal disease. Multimodality surgically based therapies may extend survival in select patients, however, local relapse after resection is common. Novel intraoperative adjunctive therapies including heated intraoperative chemotherapy (HIOC), heated intraoperative povidone-iodine (PVP-I), and photodynamic…
Read MoreThree-dimensional finite-element based deformable image registration for evaluation of pleural cavity irradiation during photodynamic therapy
Medical Physics 2017 April [Epub ahead of print] [Link] Penjweini R, Kim MM, Zhu TC Abstract PURPOSE: Photodynamic therapy (PDT) is used after surgical resection to treat the microscopic disease for malignant pleural mesothelioma and to increase survival rates. As accurate light delivery is imperative to PDT efficacy, the deformation of the pleural volume during…
Read MoreExtended Pleurectomy-Decortication-Based Treatment for Advanced Stage Epithelial Mesothelioma Yielding a Median Survival of Nearly Three Years
The Annals of Thoracic Surgery 2017 March [Epub November 5] [Link] Friedberg JS, Simone CB 2nd, Culligan MJ, Barsky AR, Doucette A, McNulty S, Hahn SM, Alley E, Sterman DH, Glatstein E, Cengel KA Abstract BACKGROUND: The purpose of this study was to assess survival for patients with malignant pleural mesothelioma (MPM), epithelial subtype, utilizing…
Read MoreReal-time light dosimetry for intra-cavity photodynamic therapy: Application for pleural mesothelioma treatment
Photodiagnosis and photodynamic therapy 2017 February 22 [Epub ahead of print] [Link] Betrouni N, Munck C, Bensoltana W, Baert G, Dewalle-Vignion AS, Scherpereel A, Mordon S Abstract Complete and homogeneous illumination of the target is necessary for the success of a photodynamic therapy (PDT) procedure. In most applications, light dosimetry is done using detectors placed…
Read MoreA Comparison of Singlet Oxygen Explicit Dosimetry (SOED) and Singlet Oxygen Luminescence Dosimetry (SOLD) for Photofrin-Mediated Photodynamic Therapy
Cancers (Basel) 2016 December 6 [Link] Kim MM, Penjweini R, Gemmell NR, Veilleux I, McCarthy A, Buller GS, Hadfield RH, Wilson BC, Zhu TC Abstract Accurate photodynamic therapy (PDT) dosimetry is critical for the use of PDT in the treatment of malignant and nonmalignant localized diseases. A singlet oxygen explicit dosimetry (SOED) model has been…
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